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Mouse Anti-Porcine Beta-Secretase 1 (BACE) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for porcine beta-secretase 1. It is purified by affinity chromatography. It can be applied to WB assay of porcine beta-secretase 1.
Specifications
Target Information
Porcine Beta-Secretase 1 (BACE1) is a type I transmembrane aspartyl protease that plays a crucial role in the production of amyloid beta-peptides (Aβ), which are central to Alzheimer's disease pathology. BACE1 cleaves the amyloid precursor protein (APP) to generate Aβ, making it a key target for therapeutic interventions in neurodegenerative research. In porcine models, BACE1 is highly conserved and expressed in neurons, oligodendrocytes, and astrocytes, similar to its expression in humans.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.