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Mouse Anti-Porcine Sarcoglycan Alpha Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for sarcoglycan alpha. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of sarcoglycan alpha.
Specifications
Target Information
Porcine sarcoglycan Alpha (pSGCA) is a component of the sarcoglycan complex, a group of transmembrane proteins that play a critical role in the stability and function of the dystrophin-glycoprotein complex within muscle cells of pigs. The sarcoglycan complex, which includes alpha, beta, gamma, and delta subunits, is essential for maintaining the integrity of the sarcolemma, the muscle cell membrane. pSGCA contributes to the proper assembly and function of the dystrophin-glycoprotein complex, which provides a mechanical link between the intracellular actin cytoskeleton and the extracellular matrix. This connection is vital for force transmission during muscle contraction and relaxation, and it protects muscle fibers from damage.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Guescini, Michele, et al. "Muscle releases alpha-sarcoglycan positive extracellular vesicles carrying miRNAs in the bloodstream." Plos one 10.5 (2015): e0125094.