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Goat Anti-Porcine Bone Morphogenetic Protein 7 (BMP7) Polyclonal Antibody

Cat. No.VD11N965

Product TypeAnimal-targeted Antibodies

Size 200 µL

Product Overview

BioVenic goat polyclonal antibody is specific for porcine bone morphogenetic protein 7. It is antigen affinity purified. It can be applied to P-ELISA and WB assays of porcine bone morphogenetic protein 7.

Specifications

Application P-ELISA; WB
Clonality Polyclonal
Classification Primary Antibody
Clone J22N8
Host Goat
Target Species Porcine
Species Reactivity Porcine
Specificity Porcine Bone Morphogenetic Protein 7
Isotype IgG
Immunogen Recombinant protein of bone morphogenetic protein 7
Purification Antigen Affinity Purified
Purity > 95% (SDS-PAGE)
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Tris Saline, pH 7.3, 0.5% Bovine Serum Albumin
Physical State Liquid

Target Information

Porcine bone morphogenetic protein 7 (BMP-7) is a member of the transforming growth factor-β (TGF-β) superfamily, known for its pleiotropic effects on bone, kidney, and other tissues. BMP-7, also called osteogenic protein-1 (OP-1), is a dimeric growth factor that binds to specific membrane-bound receptors, BMPR1 and BMPR2, to transduce signals through the Smad pathway. It plays a crucial role in bone development and repair, promoting osteogenesis and accelerating fracture healing. In addition to its role in bone, BMP-7 is involved in kidney development and has been shown to protect against renal fibrosis and diabetic nephropathy.

Target Porcine Bone Morphogenetic Protein 7
Target Synonym BMP7
Gene ID 492315
UniProt ID A5GFN2

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Kim, Seonghun, et al. "Micellized protein transduction domain-bone morphogenetic Protein-7 efficiently blocks renal fibrosis via inhibition of transforming growth factor-beta-mediated epithelial-mesenchymal transition." Frontiers in Pharmacology 11 (2020): 591275.
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