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Rabbit Anti-Canine Endothelin 1 (EDN1) Polyclonal Antibody

Cat. No.VD11N856

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for canine endothelin 1. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of canine endothelin 1.

Specifications

Application WB; IHC; IF/ICC
Clonality Polyclonal
Classification Primary Antibody
Clone J16N13
Host Rabbit
Target Species Canine
Species Reactivity Canine
Specificity Canine Endothelin 1
Immunogen Recombinant protein of endothelin 1
Purification Protein A Purified
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Canine endothelin 1 (ET-1) is a potent vasoconstrictive peptide that plays a significant role in regulating cardiovascular development and homeostasis in dogs. Originally identified as a factor released by vascular endothelial cells, ET-1 is now recognized as a product of numerous cells and tissues, including monocytes and macrophages. It acts as a mitogen for vascular-smooth muscle cells, modulates the expression of adhesion molecules on endothelial cells, and is a chemoattractant and modulator of immune cell function.

Target Canine Endothelin 1
Target Synonym ET-1; EDN1; Preproendothelin-1; PPET1
Gene ID 403424
UniProt ID P13206

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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