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Mouse Anti-Porcine Wolfram Syndrome 1 (WFS1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for wolfram syndrome 1. It is affinity purified by protein G. It can be applied to WB and ELISA assays of wolfram syndrome 1.
Specifications
Target Information
Porcine wolfram syndrome 1 (PWFS1) refers to the porcine homolog of the human Wolfram Syndrome 1 gene (WFS1), which is associated with wolfram syndrome, also known as DIDMOAD syndrome. This is a rare genetic disorder characterized by diabetes insipidus, diabetes mellitus, optic atrophy, and deafness. PWFS1 is a transmembrane protein that plays a crucial role in the endoplasmic reticulum (ER) quality control, calcium homeostasis, and the regulation of vesicular trafficking. Mutations in the WFS1 gene can lead to the misfolding of proteins, which in turn can disrupt cellular functions and contribute to the development of wolfram syndrome.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.