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Mouse Anti-Chicken Transcription Factor IIB (TFIIH) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for chicken transcription factor IIB. It can be applied to WB, IHC, IF and ICC assays of chicken transcription factor IIB.
Specifications
Target Information
Transcription factor IIB (TFIIB) is a global transcription initiation factor that plays a pivotal role in the process of transcription by RNA polymerase II. It is one of the general transcription factors essential for the initiation of gene expression in eukaryotic cells. TFIIB is involved in the formation of the pre-initiation complex, which is a crucial step in the transcription of DNA into RNA. It interacts with other transcription factors and the core promoter region of DNA to help position the RNA polymerase II at the correct location for initiating transcription.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Baek, Hwa Jin, et al. "Human Mediator enhances basal transcription by facilitating recruitment of transcription factor IIB during preinitiation complex assembly." Journal of Biological Chemistry 281.22 (2006): 15172-15181.