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Mouse Anti-Bovine Mothers Against Decapentaplegic Homolog 5 (SMAD5) Monoclonal Antibody

Cat. No.VD12N419

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for bovine mothers against decapentaplegic homolog 5. It is purified by affinity chromatography. It can be applied to WB, IF and FCM assays of bovine mothers against decapentaplegic homolog 5.

Specifications

Application WB; IF; FCM
Clonality Monoclonal
Classification Primary Antibody
Clone M5N33
Host Mouse
Target Species Bovine
Species Reactivity Bovine
Specificity Bovine Mothers Against Decapentaplegic Homolog 5
Immunogen Recombinant protein of mothers against decapentaplegic homolog 5
Purification Purified by Affinity Chromatography
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer 0.1M Tris-Glycine, pH 7.4, with 150 mM NaCl and 50% glycerol
Physical State Liquid

Target Information

Bovine Mothers Against Decapentaplegic Homolog 5 (SMAD5), also known as MADH5 or JV5-1, is a transcriptional regulator activated by BMP type I receptor kinases. It plays a critical role in the BMP signaling pathway, which is involved in embryonic development, cell differentiation, angiogenesis, and tissue homeostasis. SMAD5 is phosphorylated upon BMP ligand binding to its receptors, forming a complex with SMAD4 that translocates to the nucleus and acts as a transcription factor. This protein is also involved in energy metabolism regulation by promoting mitochondrial respiration and glycolysis in response to cytoplasmic pH changes.

Target Bovine Mothers Against Decapentaplegic Homolog 5
Target Synonym SMAD5
Gene ID 768050
UniProt ID A0A3Q1M3K3

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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