Mouse Anti-Canine Huntingtin-Interacting Protein (HIP) Monoclonal Antibody

HIP, also known as huntingtin-interacting protein, is a multifunctional protein that plays a significant role in various cellular processes, including endocytosis, protein trafficking, and signal transduction. It is highly conserved across species and is characterized by its ability to interact with a wide range of binding partners, including the protein huntingtin, which is associated with huntington's disease. The interaction of HIP with huntingtin is particularly important, as it is believed to modulate the aggregation and clearance of mutant huntingtin proteins, which are implicated in the pathogenesis of Huntington's disease. Additionally, HIP has been implicated in the regulation of cell cycle progression and apoptosis, further highlighting its importance in maintaining cellular homeostasis.