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Mouse Anti-Canine IDH3A Monoclonal Antibody

Cat. No.VD11N120

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine IDH3A. It can be applied to WB, ICC/IF and FACS assays of canine IDH3A.

Specifications

Application WB; ICC/IF; FACS
Clonality Monoclonal
Classification Primary Antibody
Clone S13N72
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine IDH3A
Isotype IgG2
Immunogen Recombinant protein of IDH3A
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, 1% BSA, 50% Glycerol
Physical State Liquid

Target Information

Canine IDH3A, or isocitrate dehydrogenase 3 (NAD+) alpha subunit, is a critical component of the IDH3 heterotetramer in the TCA cycle, catalyzing the oxidative decarboxylation of isocitrate to α-ketoglutarate (α-KG). This enzyme plays a significant role in cellular energy metabolism and is implicated in the regulation of cellular redox status. In the context of cancer, IDH3A has been identified as being upregulated in hepatocellular carcinoma tissues and is associated with tumor size and clinicopathologic stage, suggesting its potential involvement in malignant tumor progression. The identification of IDH3A as a potential therapeutic target for HCC highlights its importance in the pathogenesis of cancer and its role in cellular processes such as migration and invasion.

Target Canine IDH3A
Target Synonym Isocitric dehydrogenase subunit alpha
Gene ID 479066
UniProt ID P54836

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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