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Rabbit Anti-Porcine Coagulation Factor XII (F12) Polyclonal Antibody

Cat. No.VD11N623

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for porcine coagulation factor XII. It is affinity purified by protein G. It can be applied to ELISA assay of porcine coagulation factor XII.

Specifications

Application ELISA
Clonality Polyclonal
Classification Primary Antibody
Clone J6N4
Host Rabbit
Target Species Porcine
Species Reactivity Porcine
Specificity Porcine Coagulation Factor XII
Isotype IgG
Immunogen Recombinant protein of coagulation factor XII
Purification Protein G Purified
Purity > 95%
Conjugation Unconjugated
Preservative and Stabilizer 0.03% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Porcine coagulation factor XII (F12) is a serum glycoprotein that plays multiple roles in initiating blood coagulation, fibrinolysis, and the production of bradykinin and angiotensin. It is primarily produced in the liver and circulates in plasma as a single-chain zymogen. Upon contact with negatively charged surfaces, FXII is converted into the active form, FXIIa, which initiates the intrinsic blood coagulation pathway by activating factor XI. Additionally, FXIIa activates the kallikrein-kinin system, leading to the release of bradykinin, which has vasodilatory and pro-inflammatory effects.

Target Porcine Coagulation Factor XII
Target Synonym F12
Gene ID 397474
UniProt ID O97507

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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