Mouse Anti-Porcine Hexokinase (HXK) II Monoclonal Antibody

Hexokinase II (HXK II) is a key enzyme in the metabolic pathway, primarily responsible for catalyzing the first step of glycolysis-the phosphorylation of glucose to glucose-6-phosphate. This reaction is essential for initiating the breakdown of glucose for energy production. HXK II is particularly notable for its high affinity for its substrate, glucose, and its presence predominantly in the liver and other tissues with high metabolic activity. This enzyme plays a crucial role in regulating glucose metabolism, and its activity is tightly linked to the cellular energy state. HXK II is known to interact with the outer mitochondrial membrane, where it senses changes in the energy status of the cell, such as the levels of ATP and ADP. This interaction modulates its activity, allowing for the fine-tuning of glucose uptake and utilization in response to cellular energy demands.