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Rabbit Anti-Bovine Insulin Like Growth Factor Binding Protein 3 (IGFBP3) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine insulin like growth factor binding protein 3. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of bovine insulin like growth factor binding protein 3.
Specifications
Target Information
Bovine insulin-like growth factor binding protein 3 (IGFBP-3) is a key protein in the IGF pathway, functioning both in IGF-dependent and IGF-independent manners. IGF-dependent roles include its endocrine role in the delivery of IGFs from the site of synthesis to target cells with IGF receptors and the activation of downstream signaling. Independent of IGFs, IGFBP-3 interacts with extracellular matrix proteins and plasma membrane proteins, translocating through the plasma membrane into the cytoplasm and nucleus. The C-terminal domain of IGFBP-3 can undergo cell penetration, making it a potential carrier for drugs or genes into cells.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.