Mouse Anti-Porcine Interleukin 17A (IL17A) Monoclonal Antibody

Porcine interleukin 17A (IL-17A) is a pro-inflammatory cytokine that plays a significant role in the immune response, particularly in the context of inflammation and host defense against pathogens. It is produced by various immune cells, including T-helper 17 (Th17) cells, and is known to stimulate the release of other cytokines, chemokines, and matrix metalloproteinases (MMPs) from stromal, innate, and adaptive immune cells. IL-17A contributes to the activation and recruitment of immune cells to the site of infection, promoting neutrophil accumulation and enhancing defense against invasive pathogens. This cytokine is also associated with the regulation of protective responses at mucosal and epithelial surfaces, including the promotion of epithelial barrier function through the stimulation of molecules like beta-defensins, S100 proteins, and lipocalin-2 (Lcn2).