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Mouse Anti-Canine Lipopolysaccharide Binding Protein (LBP) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine Lipopolysaccharide Binding Protein. It can be applied to IP and ELISA assays of canine Lipopolysaccharide Binding Protein.
Specifications
Target Information
Canine lipopolysaccharide binding protein (LBP) is encoded by the LBP gene and plays a pivotal role in immune responses to infections caused by Gram-negative bacteria. It is significantly increased during acute-phase responses and has a high affinity for the lipid A portion of LPS, facilitating the binding of LPS to CD14 on monocytes and macrophages, which in turn stimulates the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and IL-6. These cytokines are involved in the pathogenesis of endotoxin shock and multiple organ failure.
Shipping and Storage
This product is shipped with wet ice packs. Store at 4°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.