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Rabbit Anti-Canine IL-21 Polyclonal Antibody
Product Overview
BioVenic rabbit anti-canine IL-21 polyclonal antibody is specific for canine IL-21. It was produced in rabbit hybridoma and protein A purified. It can be applied to ELISA assay.
Specifications
Target Information
Canine Interleukin 21 (IL-21) is a protein that in canines (dogs) is encoded by the IL21 gene. It plays several crucial roles in the immune response. This cytokine induces a range of immune responses such as maturation and proliferation of natural killer cells, stimulation of cytotoxic T cells, production of immunoglobulin in B cells, and differentiation of CD4+ T cells into Th17 cells. Canine IL-21 may be implicated in various immune-related diseases, including inflammatory, autoimmune conditions, and cancer. Defects or dysregulation in this pathway can lead to an inappropriate immune response, potentially causing chronic inflammation, autoimmunity, or a weakened response to infections.
Shipping and Storage
This product is shipped with dry ice. Store at -20°C to -80°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Wei, Lai, et al. "IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner." Journal of Biological Chemistry 282.48 (2007): 34605-34610.