Mouse Anti-Porcine GTPase Activating Protein Sh3 Domain Binding Protein 1 (G3BP1) Monoclonal Antibody

Porcine GTPase activating protein Sh3 domain binding protein 1 (pG3BP1) is an essential regulatory protein involved in the control of intracellular signaling pathways. It is known for its role in binding to the Src homology 3 (SH3) domains of various signaling proteins, thereby modulating their activity. pG3BP1 is implicated in a range of cellular processes, including actin cytoskeleton remodeling, endocytosis, and mRNA translation regulation. Its interaction with GTPase activating proteins (GAPs) is particularly significant, as it helps to regulate the GTPase cycle, which is crucial for controlling the switch between the active and inactive states of small GTPases. These enzymes are vital for many cellular functions, including signal transduction, cell growth, and differentiation. Targeting pG3BP1 in pigs could offer insights into the complex interplay of intracellular signaling mechanisms and may have implications for the study and treatment of diseases that involve dysregulation of these pathways.