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Mouse Anti-Canine Glycine N-Methyltransferase (GNMT) Monoclonal Antibody

Cat. No.VD11N172

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine glycine N-methyltransferase. It can be applied to WB and FACS assays of canine glycine N-methyltransferase.

Specifications

Application WB; FACS
Clonality Monoclonal
Classification Primary Antibody
Clone S15N12
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Glycine N-Methyltransferase
Isotype IgG3
Immunogen Recombinant protein of glycine N-methyltransferase
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, 1% BSA, 50% Glycerol
Physical State Liquid

Target Information

Canine glycine N-methyltransferase (GNMT) is an enzyme that plays a crucial role in regulating the methylation cycle by catalyzing the transfer of a methyl group from S-adenosylmethionine (SAM) to glycine, forming sarcosine and S-adenosylhomocysteine (SAH). This process is significant as it influences the cellular methylation reactions, including DNA methylation and protein methylation, which are vital for gene regulation and protein function. GNMT also serves as a folate-binding protein and has been implicated in the prevention of DNA adduct formation by binding environmental carcinogens, thus playing a role in cancer prevention.

Target Canine Glycine N-Methyltransferase
Target Synonym GNMT
Gene ID 474905
UniProt ID A0A8I3RV36

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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