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Mouse Anti-Porcine Hexokinase 1 Monoclonal Antibody

Cat. No.VD10N36

Product TypeAnimal-targeted Antibodies

Size 100ug

Product Overview

BioVenic mouse monoclonal antibody is specific for hexokinase 1. It is affinity purified by protein A. It can be applied to WB, IP, IHC and Indirect ELISA assays of hexokinase 1.

Specifications

Application WB; IP; IHC; Indirect ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone O11N36
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Hexokinase 1
Isotype IgG2
Immunogen Recombinant protein of hexokinase 1
Purification Protein A Purified
Concentration 1 mg/mL
Conjugation Unconjugated
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Porcine hexokinase 1 (HK1) is a key enzyme that catalyzes the first step of glucose metabolism, converting glucose to glucose-6-phosphate. This process is essential for cellular energy production and is tightly linked to the regulation of glucose metabolism and inflammation. In pigs, HK1 plays a significant role in the metabolic fate of glucose, with its cellular localization being crucial for determining the metabolic pathways glucose can be channeled into, such as glycolysis or the pentose phosphate pathway (PPP). In pigs, understanding the role of HK1 in glucose metabolism and its impact on inflammation and neurological health can provide valuable insights for veterinary medicine and potentially inform human therapeutic strategies. The multifaceted role of HK1 in cellular metabolism and its implications in disease make it an important target for further research in both health and disease.

Target Hexokinase 1
Target Synonym Brain form hexokinase
Gene ID 100152344
UniProt ID F1SUF2

Shipping and Storage

This product is shipped with ice gel packs. Store at -80°C on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Saraiva, Leonardo M., et al. "Amyloid-β triggers the release of neuronal hexokinase 1 from mitochondria." PloS one 5.12 (2010): e15230.
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