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Porcine Serine-protein Kinase ATM (ATM) ELISA Kit-Sandwich

Name: Porcine Serine-protein Kinase ATM (ATM) ELISA Kit-Sandwich
SKU: EK12F525
Rating: 5 (1 reviews)

Cat. No.EK12F525

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Porcine Serine-protein Kinase ATM (ATM) ELISA Kit-Sandwich is designed for the quantitative determination of Porcine Serine-protein Kinase ATM (ATM) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Porcine ATM.

Target Species Swine

Species Reactivity Swine

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 270 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Serine-protein kinase ATM, also known as Ataxia-telangiectasia mutated (ATM), is a serine/threonine protein kinase that plays a crucial role in cellular responses to DNA double-strand breaks (DSBs), oxidative stress, topoisomerase cleavage complexes, splicing intermediates, R-loops, and, in some cases, single-strand DNA breaks. Serine-protein Kinase ATM is encoded by the ATM gene in pigs. ATM activity plays a central role in regulating checkpoint mechanisms and is influenced by chromatin structure.

Target/Biomarker Porcine ATM

Target Synonym Serine-protein kinase ATM; Ataxia telangiectasia mutated homolog; A-T mutated homolog; ATM; 2.7.11.1

Gene ID 100101922

UniProt ID Q6PQD5

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Wang, H. et al. Effect of ATM and HDAC Inhibition on Etoposide-Induced DNA Damage in Porcine Early Preimplantation Embryos. PloS one. 2015, 10: e0142561.