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Recombinant Canine Apoptosis Regulator Bcl-2 (BCL2)
Product Overview
BioVenic's Recombinant Canine Apoptosis Regulator Bcl-2 (BCL2) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 26.5 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
In veterinary medicine, Bcl-2 (BCL2) is a key apoptosis regulator that belongs to the Bcl-2 protein family, controlling apoptosis by regulating the integrity of the mitochondrial outer membrane. Bcl-2 plays a crucial role in cell survival by interacting with pro-apoptotic proteins such as BAX, thereby inhibiting apoptosis. In canine diseases, Bcl-2 expression is associated with various pathological processes. For example, high Bcl-2 levels in certain canine tumors are linked to increased cell proliferation and resistance to apoptosis. Additionally, the Bcl-2/BAX ratio can be used to detect early apoptosis in canine granulosa cells. Thus, Bcl-2 is valuable for studying and diagnosing canine diseases.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.