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Recombinant Canine Claudin 18 (CLDN18), N-8His
Product Overview
BioVenic's Recombinant Canine Claudin 18 (CLDN18), N-8His is a recombinant protein expressed from E. coli expression system. Its predicted molecular weight is 20 kDa. The purity is greater than 95% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL). It has an N-terminal 8His tag.
Specifications
Target Information
The CLDN18 gene encodes a protein known as Claudin-18 (CLDN18) in dogs. It belongs to the claudin group of proteins, which form tight junction strands in epithelial cells. CLDN18 plays a major role in the tight junction-specific obliteration of the intercellular space through calcium-independent cell-adhesion activity. CLDN18 has two isoforms, A1 and A2. Research has shown that the CLDN18.2 protein sequence is highly conserved, in particular with regard to functionally relevant domains in mouse, rat, rabbit, dog, monkey and human and also in lizards.
Shipping and Storage
This product is shipped with dry ice. It should be stored at -80°C, stable for 6 months after receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Please avoid freeze-thaw cycles.