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Recombinant Canine Matrix Metalloproteinase-9 (MMP9), N-His

Cat. No.AP9C583

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Canine Matrix Metalloproteinase-9 (MMP9), N-His is a recombinant protein expressed from Yeast. Its predicted molecular weight is 68.3 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Canine
Expression System Yeast
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 68.3 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.

Target Information

Canine matrix metalloproteinase-9 (MMP-9) is a proteolytic enzyme that plays a significant role in tissue remodeling and is associated with various pathological conditions in dogs, including cancer progression and inflammation. It is involved in the degradation of extracellular matrix components, which is crucial for physiological processes such as wound healing and tissue repair, as well as pathological processes like tumor invasion and metastasis. In canine mammary tumors, MMP-9 expression has been linked to tumor malignancy, proliferation rate, and histologic grade, suggesting its importance as a prognostic factor.

Protein Canine Matrix Metalloproteinase-9 (MMP9)
Protein Synonym 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B (GELB); MMP9Matrix metalloproteinase-9; MMP-9; EC 3.4.24.35; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB
Gene ID 403885
UniProt ID O18733

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.
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