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Recombinant Canine Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1), N-His

Product Overview

BioVenic's Recombinant Canine Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1), N-His is a recombinant protein expressed from HEK293 Cells. Its predicted molecular weight is 16.2 kDa. The purity is>95% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL).

Specifications

Type Recombinant Protein

Species Canine

Expression System HEK293 Cells

Biological Activity Active

Purity >95% (SDS-PAGE)

Endotoxin <1 EU/μg (LAL)

Predicted Molecular Weight 16.2 kDa

Physical State Lyophilized

Formulation PBS, pH 7.4.

Target Information

Neurotrophic receptor tyrosine kinase 1 is encoded by the NTRK1 gene in dogs. Some studies have demonstrated an association between mutations in the neurotrophic tyrosine kinase receptor type 1 and congenital insensitivity to pain with anhidrosis.

Protein Canine Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1)

Protein Synonym neurotrophic receptor tyrosine kinase 1, TRKA, high affinity nerve growth factor receptor, tropomyosin-related kinase A

Gene ID 490404

EC No. 2.7.10.1

Shipping and Storage

This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.

References

Gao, L. et al. Oral and craniofacial manifestations and two novel missense mutations of the NTRK1 gene identified in the patient with congenital insensitivity to pain with anhidrosis. PloS one. 2013, 8: e66863.