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Recombinant Clostridium chauvoei Putative Hemolysin A, N-GST

Cat. No.VG9C227

Product TypeVeterinary Antigens

Size

Product Overview

BioVenic's Recombinant Clostridium chauvoei Putative Hemolysin A, N-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 60.0 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bacterium
Expression System E.coli
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 60.0 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

In the veterinary field, Clostridium chauvoei putative hemolysin A is a significant toxin, a β-barrel pore-forming toxin belonging to the leucocidin superfamily of bacterial toxins. CctA is one of the main toxins causing blackleg disease in animals, with strong hemolytic and cytotoxic properties, showing high cytotoxicity to the bovine epithelial cell line ECaNEp. In vaccine development, CctA serves as a major protective antigen, inducing neutralizing antibodies against infections caused by C. chauvoei, making it a key component of vaccines and immunization strategies.

Protein Clostridium chauvoei Putative Hemolysin A
Protein Synonym beta-channel forming cytolysin; Alpha-hemolysin; CCTA; Clostridium chauvoei toxin A
UniProt ID S6ERN0

Shipping and Storage

This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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