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Recombinant Feline Brain-derived Neurotrophic Factor (BDNF)
Product Overview
BioVenic's Recombinant Feline Brain-derived Neurotrophic Factor (BDNF) is a recombinant protein expressed from E. coli expression system. Its predicted molecular weight is 13 kDa. The purity is greater than 95% (SDS-PAGE). The endotoxin level is <0.01 EU/μg (LAL).
Specifications
Target Information
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. BDNF promotes the survival, growth, and differentiation of neurons, BDNF and TrkB are major regulators of synaptic transmission and plasticity at adult synapses in many regions of the CNS. According to research, the expression levels of BDNF and TrkB decrease with age in the primary visual cortex of cats.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -20°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -20°C for 3 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Dissolve the lyophilized protein in distilled water. Avoid mixing by vortexing or pipetting. It is not recommended to reconstitute to a concentration < 100 μg/mL. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Tong, C. & Cao, S. Study on the mechanism of visual aging in cats' primary visual cortex based on BDNF-TrkB signal pathway. Scientific reports. 2022, 12: 10576.