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Recombinant Feline Survival of Motor Neuron Protein (SMN1)
Product Overview
BioVenic's Recombinant Feline Survival of Motor Neuron Protein (SMN1) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 31.3 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Feline survival of motor neuron protein (SMN1) is a crucial protein involved in maintaining the health and function of motor neurons in cats. It is essential for the assembly of small nuclear ribonucleoproteins (snRNPs), which are critical for pre-mRNA splicing. In feline models, SMN1 deficiency is associated with spinal muscular atrophy (SMA), a severe neuromuscular disorder characterized by progressive muscle weakness and atrophy. SMN1 also plays a role in axonal growth and maintenance, ensuring proper neuronal function and connectivity. Additionally, SMN1 is involved in RNA metabolism and lysosomal function, highlighting its multifaceted role in cellular health.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.