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Recombinant Canine Programmed Cell Death Protein 1 (PD1), N-His
Product Overview
BioVenic's Recombinant Canine Programmed Cell Death Protein 1 (PD1), N-His is a recombinant protein expressed from E.coli expression system. Its predicted molecular weight is 35.3 kDa. The purity is>95% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL). It can be used as a positive control or as an immunogen.
Specifications
Target Information
Programmed cell death protein 1 (PD-1) functions as an immune checkpoint, playing a crucial role in preventing autoimmunity through two primary mechanisms. Firstly, it induces apoptosis (programmed cell death) of antigen-specific T-cells within lymph nodes. Secondly, it decreases apoptosis in regulatory T cells, which are anti-inflammatory and suppressive in nature.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 4 weeks at 2-8°C, for 12 months at -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH 7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex. Aliquote the reconstituted solution to minimise freeze-thaw cycles.