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Recombinant Bovine Fibronectin Type III Domain Containing 5 (FNDC5), C-Fc
Product Overview
BioVenic's Recombinant Bovine Fibronectin Type III Domain Containing 5 (FNDC5), C-Fc is a recombinant protein expressed from Mammalian expression system. Its predicted molecular weight is 40 kDa. The purity is greater than 95% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL). It has a C-terminal Fc tag.
Specifications
Target Information
Fibronectin type III domain-containing protein 5 is encoded by the FNDC5 gene in cattle. It is a transmembrane protein that has been characterised as a precursor of an exercise-induced myokine called irisin. The production of irisin is similar to the shedding and release of other hormones and hormone-like polypeptides, such as epidermal growth factor and TGF-alpha, from transmembrane precursors.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -20°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -20°C for 3 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Dissolve the lyophilized protein in distilled water. Avoid mixing by vortexing or pipetting. It is not recommended to reconstitute to a concentration < 100 μg/mL. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Komolka, K. et al. Locus characterization and gene expression of bovine FNDC5: is the myokine irisin relevant in cattle? PloS one. 2014, 9: e88060.