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Recombinant Feline Cytochrome P450 1A2 (CYP1A2)

Cat. No.AP2C201

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Feline Cytochrome P450 1A2 (CYP1A2) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 57.7 kDa. The purity is>85% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Feline
Expression System E.coli
Purity >85% (SDS-PAGE)
Predicted Molecular Weight 57.7 kDa
Physical State Lyophilized
Formulation Tris/PBS-based buffer, 6% Trehalose.

Target Information

Feline cytochrome P450 1A2 (CYP1A2) is a key enzyme involved in the metabolism of various drugs and endogenous compounds in cats. It plays a crucial role in the biotransformation of xenobiotics and is one of the major CYP isoforms in the feline liver. CYP1A2 is responsible for metabolizing a wide range of substances, including medications, toxins, and essential endogenous compounds such as steroids and fatty acids. Genetic polymorphisms in feline CYP1A2 can affect its metabolic activity, influencing drug efficacy and the risk of adverse reactions. Understanding these variations is important for optimizing drug dosing and preventing adverse effects in veterinary medicine.

Protein Feline Cytochrome P450 1A2 (CYP1A2)
Protein Synonym CYPIA2; Cholesterol 25-hydroxylase
Gene ID 554345
UniProt ID Q5KQT6

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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