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Recombinant Goat Metalloproteinase Inhibitor 1 (TIMP1), N-His

Cat. No.AP1C181

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Goat Metalloproteinase Inhibitor 1 (TIMP1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Goat
Expression System E.coli
Purity >97% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight N/A
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Target Information

Goat metalloproteinase inhibitor 1 (TIMP-1) is a glycoprotein expressed in various tissues and is a natural inhibitor of matrix metalloproteinases (MMPs). It plays a crucial role in maintaining the balance of the extracellular matrix by inhibiting the degradation of MMPs. TIMP-1 also has MMP-independent functions, including the modulation of angiogenesis, promotion of cell proliferation, and inhibition of apoptosis. It is involved in several biological processes such as tissue repair, immune responses, and cancer progression. Abnormalities in TIMP-1 expression are associated with various diseases, including cancer and inflammatory conditions.

Protein Goat Metalloproteinase Inhibitor 1 (TIMP1)
Protein Synonym SFD; TIMP Metallopeptidase Inhibitor 3; Metallopeptidase Inhibitor 3; Sorsby Fundus Dystrophy; Pseudoinflammatory
Gene ID 100860924
UniProt ID A0A0C5Q4X5

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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