Recombinant Mesomycoplasma ovipneumoniae DHH family phosphoesterase, N-His-SUMO

In the veterinary field, the function of Mesomycoplasma ovipneumoniae DHH family phosphoesterase, particularly the PdhD protein, is primarily associated with bacterial adhesion, invasion, and immune evasion. PdhD is a membrane-anchored surface protein implicated in the pathogenic processes of Mesomycoplasma ovipneumoniae. Studies have shown that PdhD can bind to plasminogen in a dose-dependent manner, suggesting its involvement in bacterial adhesion. Additionally, PdhD is involved in biofilm formation, which is crucial for bacterial persistence and drug resistance. Anti-PdhD antibodies can inhibit bacterial adhesion and biofilm formation, indicating that PdhD is a potential vaccine target for developing new prevention and treatment strategies against M. ovipneumoniae infections.