Recombinant Mouse C-X-C Motif Chemokine 16 (Cxcl16), C-His

Mouse C-X-C Motif Chemokine 16 (Cxcl16) is a chemokine belonging to the CXC family that plays a crucial role in immune responses by mediating the chemotaxis of various immune cells. It binds to the chemokine receptor CXCR6 and is involved in processes such as inflammation, tissue repair, and host defense against pathogens. In mice, Cxcl16 has been implicated in several disease models. For example, it is involved in the pathogenesis of renal injury and fibrosis by regulating the infiltration of macrophages and T cells. Cxcl16 also plays a role in liver immune responses and has been shown to influence the progression of diseases like acetaminophen-induced hepatotoxicity. Additionally, Cxcl16 is associated with the development of atherosclerosis and can act as a biomarker for certain inflammatory conditions. Researchers study Cxcl16 to understand its functions in immune cell trafficking and inflammation, which can lead to the development of targeted therapies for related diseases.