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Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 18 (TNFRSF18), C-Fc-His
Product Overview
BioVenic's Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 18 (TNFRSF18), C-Fc-His is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 25.3 kDa. The purity is>90%.
Specifications
Target Information
Mouse Tumor Necrosis Factor Receptor Superfamily Member 18, or TNFRSF18, is a tumor necrosis factor receptor involved in immune response regulation. In mouse experiments, TNFRSF18 is studied for its roles in immune cell activation and immune-related diseases. TNFRSF18 binds to its ligand, GITL, to provide costimulatory signals that enhance T cell activation and proliferation. This interaction is crucial for the development of effective immune responses against pathogens and tumors. In autoimmune diseases, overexpression of TNFRSF18 has been associated with exaggerated immune responses and tissue inflammation. Targeting the TNFRSF18-GITL pathway has emerged as a potential therapeutic strategy to modulate immune responses in various clinical settings, including transplantation and inflammatory disorders.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.