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Recombinant Sheep Tumor Necrosis Factor (TNF-alpha), N-His

Cat. No.AP1C136

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Sheep Tumor Necrosis Factor (TNF-alpha), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 21.0 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Sheep
Expression System E.coli
Purity >90% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight 21.0 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Target Information

Sheep tumor necrosis factor (TNF) is a multifunctional cytokine that plays a significant role in the immune and inflammatory responses of sheep. It is involved in the elimination of infectious agents and is critical in the pathogenesis of diseases. TNF is produced by various cell types, including macrophages and lymphocytes, and it activates several cell signaling pathways associated with cell survival, growth, and differentiation. In sheep, TNF is particularly important for its role in host defense against parasitic infections and its contribution to the regulation of immune cell functions.

Protein Sheep Tumor Necrosis Factor (TNF-alpha)
Protein Synonym DIF; TNF-A; TNFSF2; Cachectin; Tumor Necrosis Factor Ligand Superfamily Member 2
Gene ID 443540
UniProt ID A5YBV0

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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