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Bovine Monofunctional C1-Tetrahydrofolate Synthase, Mitochondrial (MTHFD1L) ELISA Kit-Sandwich

Name: Bovine Monofunctional C1-Tetrahydrofolate Synthase, Mitochondrial (MTHFD1L) ELISA Kit-Sandwich
SKU: EK11F787
Rating: 5 (1 reviews)

Cat. No.EK11F787

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Bovine Monofunctional C1-Tetrahydrofolate Synthase, Mitochondrial (MTHFD1L) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Monofunctional C1-Tetrahydrofolate Synthase, Mitochondrial (MTHFD1L) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Bovine MTHFD1L.

Target Species Bovine

Species Reactivity Bovine

Detection Range 0.312-20 ng/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 270 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

MTHFD1L (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like) is an enzyme involved in tetrahydrofolate (THF) synthesis in mitochondria. Unlike its counterpart, MTHFD1, which has trifunctional methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase, and formyltetrahydrofolate synthetase enzymatic activities, MTHFD1L only has formyltetrahydrofolate synthetase activity. Bovine Monofunctional C1-Tetrahydrofolate Synthase, Mitochondrial is encoded by the MTHFD1L gene in cattle. The MTHFD1L enzyme is present in the mitochondria of normal embryonic tissues and embryonic fibroblast cell lines.

Target/Biomarker Bovine MTHFD1L

Target Synonym methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like; monofunctional C1-tetrahydrofolate synthase, mitochondrial; formyltetrahydrofolate synthetase

Gene ID 534296

UniProt ID Q0VCR7

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Pike, S. T. et al. Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos. The Journal of biological chemistry. 2010, 285: 4612-4620.