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Bovine Camp-Dependent Protein Kinase Type I-Alpha Regulatory Subunit (PRKAR1A) ELISA Kit-Sandwich

Name: Bovine Camp-Dependent Protein Kinase Type I-Alpha Regulatory Subunit (PRKAR1A) ELISA Kit-Sandwich
SKU: EK2F436
Rating: 5 (1 reviews)

Cat. No.EK2F436

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Bovine Camp-Dependent Protein Kinase Type I-Alpha Regulatory Subunit (PRKAR1A) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Camp-Dependent Protein Kinase Type I-Alpha Regulatory Subunit(PRKAR1A) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Bovine PRKAR1A.

Target Species Bovine

Species Reactivity Bovine

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 210 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

PRKAR1A, also known as cAMP-dependent protein kinase type I-alpha regulatory subunit, is an enzyme that plays a critical role in cAMP signaling in mammals. It is a critical component of type I protein kinase A (PKA), which is the main mediator of cAMP signaling. Research has shown that inactivating mutations of PRKAR1A have long been recognised as the genetic cause of Carney complex.

Target/Biomarker Bovine PRKAR1A

Target Synonym cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed];;

Gene ID 615074

UniProt ID P00514

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Rhayem, Y. et al. Functional Characterization of PRKAR1A Mutations Reveals a Unique Molecular Mechanism Causing Acrodysostosis but Multiple Mechanisms Causing Carney Complex. The Journal of biological chemistry. 2015, 290: 27816-27828.