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Bovine Major Prion Protein (PRNP) ELISA Kit-Sandwich

Name: Bovine Major Prion Protein (PRNP) ELISA Kit-Sandwich
SKU: EK12F309
Rating: 5 (1 reviews)

Cat. No.EK12F309

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Bovine Major Prion Protein (PRNP) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Major Prion Protein (PRNP) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Bovine PRNP.

Target Species Bovine

Species Reactivity Bovine

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 270 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

A prion is a misfolded protein that can induce misfolding of normal variants of the same protein and trigger cellular death. Prions can misfold sporadically, due to genetic mutations, or by exposure to an already misfolded protein. Bovine Major Prion Protein is encoded by the PRNP gene in cattle. Research has found a tentative association between PRNP promoter polymorphisms and bovine spongiform encephalopathy susceptibility in German cattle.

Target/Biomarker Bovine PRNP

Target Synonym prion protein; PrP; prn; AltPrP; major prion protein; alternative prion protein; major scrapie-associated fibril protein 1; prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia); prion protein PrP; prion protein precursor PrP

Gene ID 281427

UniProt ID P10279

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Sander, P. et al. Bovine Prion Protein Gene (PRNP) Promoter Polymorphisms Modulate PRNP Expression and May Be Responsible for Differences in Bovine Spongiform Encephalopathy Susceptibility. Journal of Biological Chemistry. 2005, 280: 37408-37414.