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Canine Transforming growth factor beta receptor 2 (TGFBR2) ELISA Kit-Sandwich

Cat. No.EK10F705

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Canine TGFBR2 ELISA Kit-Sandwich is designed for the quantitative determination of Canine TGFBR2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Canine TGFBR2.
Target Species Canine
Species Reactivity Canine
Detection Range 16-1000 pg/mL
Sensitivity 3.1 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 180 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Transforming growth factor beta receptor 2 is encoded by the TGFBR2 gene in dogs. It is an immunosuppressive cytokine that induces regulatory T cell (Tregs) differentiation and is involved in immune evasion mechanisms in cancer.

Target/Biomarker Canine TGFBR2
Target Synonym transforming growth factor beta receptor 2; TGF-beta receptor type-2; transforming growth factor beta type II receptor
Gene ID 477039
UniProt ID A0A8C0NR78

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Takeuchi, H. et al. Canine transforming growth factor-β receptor 2-Ig: A potential candidate biologic for melanoma treatment that reverses transforming growth factor-β1 immunosuppression. Frontiers in Veterinary Science. 2021, 8: 656715.
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