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Chicken Diablo IAP-binding mitochondrial protein (Diablo) ELISA Kit-Sandwich

Name: Chicken Diablo IAP-binding mitochondrial protein (Diablo) ELISA Kit-Sandwich
SKU: EK9F247
Rating: 5 (1 reviews)

Cat. No.EK9F247

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Chicken DIABLO ELISA Kit-Sandwich is designed for the quantitative determination of Chicken diablo IAP-binding mitochondrial protein (DIABLO) in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Chicken DIABLO.

Target Species Chicken

Species Reactivity Chicken

Detection Range 32-2000 pg/mL

Sensitivity 6.25 pg/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 180 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Diablo IAP-binding mitochondrial protein, also known as SMAC, is encoded by the DIABLO gene. It was reported to promote apoptosis by inhibiting IAP activity. In the mitochondria-mediated caspase-dependent apoptotic pathway, cyt-c, HtrA2/Omi, Smac/Diablo, apaf-1, PARP, and caspase-9, 3, 6, and 7 were all increased in a chicken model.

Target/Biomarker Chicken DIABLO

Target Synonym diablo IAP-binding mitochondrial protein; diablo homolog mitochondrial; diablo homolog; SMAC

Gene ID 416860

UniProt ID A0A8V1AAG0

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Guo, H. et al. Nickel chloride-induced apoptosis via mitochondria- and Fas-mediated caspase-dependent pathways in broiler chickens. Oncotarget. 2016, 7: 79747-79760.