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Equine Matrix Metalloproteinase 13 (MMP13) ELISA Kit-Sandwich

Name: Equine Matrix Metalloproteinase 13 (MMP13) ELISA Kit-Sandwich
SKU: EK12F947
Rating: 5 (1 reviews)

Cat. No.EK12F947

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Equine Matrix Metalloproteinase 13 (MMP13) ELISA Kit-Sandwich is designed for the quantitative determination of Equine Matrix Metalloproteinase 13 (MMP13) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Equine MMP13. No cross-reactivity with other relevant proteins.

Target Species Equine

Species Reactivity Equine

Detection Range 15.625-1000 pg/mL

Sensitivity 7 pg/mL

Recovery 83%-103%

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 270 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Matrix Metalloproteinase 13 (MMP-13) is a collagenase that plays a crucial role in the irreversible destruction of cartilage collagen in conditions such as osteoarthritis (OA). It is involved in tissue remodeling and extracellular matrix turnover. Matrix Metalloproteinase 13 is encoded by the MMP13 gene in horses. Research has shown that synoviocytes and chondrocytes from clinically normal and arthritic joints can express MMP-13. MMP-13 has been shown to be more sensitive to doxycycline than other MMPs.

Target/Biomarker Equine MMP13

Target Synonym CLG3;Collagenase 3

Gene ID 100009711

UniProt ID O18927

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

1. Ghasemi, S. et al. In vitro study of matrix metalloproteinases 1, 2, 9, 13 and serum amyloid A mRNAs expression in equine fibroblast-like synoviocytes treated with doxycycline. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 2018, 82: 82-88.