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Mouse Anti-Canine Tumor Protein p53 Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine tumor protein p53. It can be applied to WB assay of canine tumor protein p53.
Specifications
Target Information
p53, also known as tumor protein p53 or TP53, is a multifunctional protein that plays a central role in the regulation of the cell cycle and apoptosis. It is often referred to as the "guardian of the genome" due to its crucial function in preventing cancer formation. p53 is activated in response to DNA damage, hypoxia, and other cellular stresses, and it mediates cell cycle arrest, allowing time for DNA repair or triggering apoptosis if the damage is irreparable. The protein is involved in a wide range of cellular processes, including senescence, DNA repair, and the maintenance of genomic stability. It achieves these functions by acting as a transcription factor that regulates the expression of numerous target genes involved in cell cycle control, apoptosis, and DNA repair.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Oren, Moshe. "Regulation of the p53 tumor suppressor protein." Journal of Biological Chemistry 274.51 (1999): 36031-36034.