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Mouse Anti-Porcine Debranching RNA Lariats 1 (DBR1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for debranching RNA lariats 1. It is affinity purified by protein A. It can be applied to WB, IP, IF, IHC and ELISA assays of debranching RNA lariats 1.
Specifications
Target Information
Porcine debranching enzyme RNA lariat 1 (Dbr1) is an essential protein involved in the maturation of mRNA in cells. It is a key component of the debranching enzyme complex, which removes the lariats formed during the splicing of precursor mRNA. This process is crucial for the production of mature, functional mRNA molecules that can be translated into proteins. As a molecular target, Dbr1 is significant due to its role in the regulation of gene expression through mRNA processing. Disruptions in the function of Dbr1 can lead to aberrant mRNA splicing and maturation, which has been implicated in various diseases, including certain genetic disorders and cancers.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Buerer, Luke, et al. "The debranching enzyme Dbr1 regulates lariat turnover and intron splicing." Nature communications 15.1 (2024): 4617.