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Mouse Anti-Porcine Pleckstrin (PLEK) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for pleckstrin. It is affinity purified by protein G. It can be applied to WB, IF, IHC and ELISA assays of pleckstrin.
Specifications
Target Information
Porcine pleckstrin (pPLEK), a member of the pleckstrin family of proteins, is an important component in cellular signal transduction pathways, particularly those involving phosphoinositide binding. pPLEK plays a crucial role in various cellular processes, including cell signaling, cytoskeletal rearrangement, and membrane trafficking. This protein is known for its ability to bind to phosphatidylinositol (PI) lipids, which are key regulators of cellular functions. The interaction of pPLEK with these lipids is often mediated by its pleckstrin homology (PH) domain, allowing it to participate in the regulation of multiple signaling cascades.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Kohn, Aimee D., et al. "Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation." Journal of Biological Chemistry 271.36 (1996): 21920-21926.