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Mouse Anti-Porcine STAT3 Monoclonal Antibody

Cat. No.VD12N291

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for porcine signal transducer and activator of transcription 3. It is purified by affinity chromatography. It can be applied to WB assay of porcine signal transducer and activator of transcription 3.

Specifications

Application WB
Clonality Monoclonal
Classification Primary Antibody
Clone M4N12
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Porcine Signal Transducer and Activator of Transcription 3
Isotype IgG
Immunogen Synthesized peptide of signal transducer and activator of transcription 3
Purification Purified by Affinity Chromatography
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol and 0.5% BSA
Physical State Liquid

Target Information

Porcine STAT3 (Signal Transducer and Activator of Transcription 3) is a key regulatory protein involved in transmitting signals from the cell surface to the nucleus. It is encoded by the STAT3 gene and shares high homology with its human and murine counterparts, with 93% and 90% sequence identity, respectively. This protein is responsive to various stimuli, including growth factors and cytokines, which trigger its phosphorylation and activation. Once activated, porcine STAT3 translocates to the nucleus, where it modulates the transcription of target genes involved in cell cycle progression, apoptosis, and immune function. STAT3 is also known to inhibit apoptosis and promote cell proliferation in ovarian granulosa cells.

Target Porcine Signal Transducer and Activator of Transcription 3
Target Synonym STAT3
Gene ID 733648
UniProt ID Q19S50

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Nan, Yuchen, et al. "Interplay between Janus kinase/signal transducer and activator of transcription signaling activated by type I interferons and viral antagonism." Frontiers in immunology 8 (2017): 1758.
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