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Mouse Anti-Canine NUMB Monoclonal Antibody

Cat. No.VD11N150

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine NUMB. It can be applied to WB, ICC/IF and FACS assays of canine NUMB.

Specifications

Application WB; ICC/IF; FACS
Clonality Monoclonal
Classification Primary Antibody
Clone S14N13
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine NUMB
Isotype IgG1
Immunogen Recombinant protein of NUMB
Concentration 0.6 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, 1% BSA, 50% Glycerol
Physical State Liquid

Target Information

Canine NUMB, also known as neuronal precursor cell expressed Developmentally Down-regulated protein 8 (Numb), is a protein that plays a crucial role in neural development, particularly in the process of neurogenesis. NUMB is involved in maintaining the self-renewal properties of neural progenitor cells in the vertebrate neural tube and is essential for controlling the balance between neural stem cell proliferation and differentiation. It functions by antagonizing the Notch signaling pathway, which is critical for cell fate determination in the developing nervous system. In dogs, NUMB may serve a similar role, influencing the development and maturation of neural cells and potentially playing a role in the maintenance of neural progenitor cells.

Target Canine NUMB
Target Synonym Protein numb homolog
Gene ID 480381
UniProt ID A0A8I3NND4

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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