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Rabbit Soluble Terminal Complement Complex C5b-9 (sC5b-9) ELISA Kit-Sandwich

Cat. No.EK3F285

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Rabbit Soluble Terminal Complement Complex C5b-9 (sC5b-9) ELISA Kit-Sandwich is designed for the quantitative determination of Rabbit sC5b-9 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Rabbit sC5b-9
Target Species Rabbit
Species Reactivity Rabbit
Detection Range 0.16-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

C5b-9 plays a crucial role in inflammation by promoting cell proliferation and rescuing apoptotic cells. The assembly of C5b-9 on cell membranes leads to the formation of transmembrane channels, ultimately resulting in cell death. However, when the number of C5b-9 molecules is limited, nucleated cells can evade cell death through endocytosis and shedding of membranes containing C5b-9. The function of sC5b-9 (soluble membrane attack complex) in rabbits is primarily related to its role in the complement system. Studies have shown that an effective mechanism for the clearance of sC5b-9 exists in rabbits. The half-life of sC5b-9 in plasma of healthy rabbits is approximately 30-50 minutes.

Target/Biomarker Rabbit sC5b-9
Target Synonym MAC; Membrane Attack Complex; C5b-9; Terminal Complement Complex C5b-9; C5b9

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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