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Recombinant Bovine Cellular Tumor Antigen p53 (TP53), N-His

Cat. No.AP2C61

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Bovine Cellular Tumor Antigen p53 (TP53), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 42.4 kDa.

Specifications

Type Recombinant Protein
Species Bovine
Expression System E.coli
Purity >95% (SDS-PAGE)
Endotoxin < 10 EU/mg
Predicted Molecular Weight 42.4 kDa
Physical State Lyophilized
Formulation Tris/PBS-based buffer, 6% Trehalose.

Target Information

The bovine cellular tumor antigen p53 (TP53) is a critical tumor suppressor protein in cattle, often referred to as the "Guardian of the Genome." It plays a key role in maintaining genomic stability and regulating the cell cycle. When cells experience DNA damage or other stress signals, TP53 is activated to regulate the expression of numerous downstream genes, promoting cell cycle arrest, DNA repair, or apoptosis. Additionally, TP53 is frequently mutated in bovine urinary bladder tumors, and its dysfunction is closely associated with tumor development.

Protein Bovine Cellular Tumor Antigen p53 (TP53)
Protein Synonym Tumor suppressor p53
Gene ID 281542
UniProt ID P67939

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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