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Recombinant Swine Epithelial Cell Adhesion Molecule (TACSTD1), N-His
Product Overview
BioVenic's Recombinant Swine Epithelial Cell Adhesion Molecule (TACSTD1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 32.2 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Swine epithelial cell adhesion molecule (EpCAM) is a type I transmembrane glycoprotein that plays a crucial role in cell adhesion, proliferation, migration, and stemness, as well as in epithelial-to-mesenchymal transition (EMT) of carcinoma cells. It is overexpressed in various human epithelial-derived neoplasms and is involved in cell signaling and differentiation. EpCAM also serves as a marker for the epithelial status of primary and systemic tumor cells and is a measure for the metastatic capacity of circulating tumor cells (CTCs). Its expression and function contribute to shaping intratumor heterogeneity and partial EMT, which are major determinants of the clinical outcome of carcinoma patients.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.