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Recombinant Goat Insulin-Like Growth Factor-Binding Protein 3 (IGFBP3), N-His
Product Overview
BioVenic's Recombinant Goat Insulin-Like Growth Factor-Binding Protein 3 (IGFBP3), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Goat insulin-like growth factor binding protein 3 (IGFBP-3) is a key member of the IGFBP family, playing a crucial role in regulating the bioavailability and activity of insulin-like growth factors (IGFs) in goats. It binds to IGFs, preventing their degradation and facilitating their transport throughout the body, thereby modulating IGF interactions with their specific receptors. IGFBP-3 also functions independently of IGFs, interacting with extracellular matrix proteins and plasma membrane proteins, and can translocate into the cytoplasm and nucleus, affecting cell growth, survival, and apoptosis. This protein is essential for growth regulation and has potential implications in metabolic diseases, including cancer, in goats.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.