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Recombinant Mouse Tumor Necrosis Factor Ligand Superfamily Member 13B (TNFSF13B), N-mFc
Product Overview
BioVenic's Recombinant Mouse Tumor Necrosis Factor Ligand Superfamily Member 13B (TNFSF13B), N-mFc is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 34.2 kDa. The purity is>90%.
Specifications
Target Information
Mouse Tumor Necrosis Factor Ligand Superfamily Member 13B (TNFSF13B) is a cytokine crucial for B cell maturation and survival. It binds to receptors like BAFF-R, TACI, and BCMA, activating pathways such as NF-κB and JAK/STAT, which promote B cell proliferation and differentiation. TNFSF13B is implicated in autoimmune diseases like systemic lupus erythematosus and rheumatoid arthritis, as well as in some cancers. Its abnormal expression is associated with B cell-related pathologies, making it a potential therapeutic target for these conditions.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.